Adenomyosis occurs when the lining of the uterus (endometrium) grows into the adjacent muscular tissue of the uterus (myometrium). It is usually associated with Endometriosis. It causes the same symptoms as endometriosis though the bleeding during periods may be more prolonged and heavy in this case. Chances of conception are lower as implantation of the fertlised egg is inadequate. Unlike endometriosis medical therapy has a role to play.

Currently, UFE is only indicated for the symptoms caused by uterine fibroids. Patients with pain or abnormal bleeding caused by other problems such as adenomyosis or endometriosis are not candidates for UFE.